Ontology highlight
ABSTRACT:
SUBMITTER: Boldrin L
PROVIDER: S-EPMC3836226 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
Boldrin Luisa L Zammit Peter Steven PS Muntoni Francesco F Morgan Jennifer Elizabeth JE
Stem cells (Dayton, Ohio) 20091001 10
Changes that occur in the skeletal muscle environment with the progress of muscular dystrophies may affect stem cell function and result in impaired muscle regeneration. It has previously been suggested that the success of stem cell transplantation could therefore be dependent both on the properties of the cell itself and on the host muscle environment. Here we engrafted young and mature adult mdx-nude mice, which are the genetic homolog of Duchenne muscular dystrophy, with a small number of sat ...[more]