Ontology highlight
ABSTRACT:
SUBMITTER: Liu Y
PROVIDER: S-EPMC3836273 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Liu Yongjun Y Ordovas Jose M JM Gao Guimin G Province Michael M Straka Robert J RJ Tsai Michael Y MY Lai Chao-Qiang CQ Zhang Kui K Borecki Ingrid I Hixson James E JE Allison David B DB Arnett Donna K DK
Journal of human genetics 20080610 8
The scavenger receptor class B type 1 (SCARB1) gene is a key component in the reverse cholesterol transport pathway and thus plays an important role in lipid metabolism. Studies suggest that the SCARB1 gene may contribute to variation in plasma lipid levels at fasting; however, the results have been inconsistent, and it is unclear whether SCARB1 may also influence lipid response to dietary and pharmacologic interventions. In this study, we examined genetic variation in the SCARB1 gene in partici ...[more]