Project description:The rabbit hemorrhagic disease virus (RHDV) represents the causative agent of a highly contagious disease in rabbits that is often associated with high mortality. Because of the lack of a suitable cell culture system for RHDV, the pathogenic mechanism and replication of RHDV remains unclear. In order to analyze the pathogenic mechanism of RHDV to rabbits, we used New Zealand white rabbits infected with RHDV, collected liver tissues 32 hours after infection, and used TMT labeling for LC-MS analysis. Subsequently, it was compared and analyzed with the protein data of the liver tissue of the uninfected rabbits. Perform bioinformatics analysis on significantly different proteins. Finally, comprehensively analyze the influence of RHDV on host protein and pathway expression levels. This study provides clues to clarify the pathogenic mechanism of RHDV in rabbits.

2022-05-19 | PXD030318 | Pride

Comparative analysis of rabbit hemorrhagic disease virus (RHDV) and new RHDV2 virus antigenicity, using specific virus-like particles.

Project description: Not available

| S-EPMC4581117 | biostudies-literature

Outbreak of Rabbit Hemorrhagic Disease Virus 2 Infections, Ghana.

Project description: Not available

| S-EPMC8237895 | biostudies-literature

Rabbit hemorrhagic disease virus type 2 epidemic in a rabbit colony in Japan.

Project description: Not available

| S-EPMC8182317 | biostudies-literature

Rabbit hemorrhagic disease virus strain:Turretfield 2009

Project description:Rabbit hemorrhagic disease virus strain:Turretfield 2009 Genome sequencing and assembly