Ontology highlight
ABSTRACT:
SUBMITTER: Xu Y
PROVIDER: S-EPMC3843577 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Xu Yang Y Shi Ying Y Yuan Qi Q Liu Xuli X Yan Bin B Chen Ling L Tao Yongguang Y Cao Ya Y
Journal of experimental & clinical cancer research : CR 20131113
The principal Epstein-Barr virus (EBV) oncoprotein, latent membrane protein 1 (LMP1) is strongly associated with nasopharyngeal carcinoma (NPC), a prevalent cancer in China. The epidermal growth factor receptor (EGFR) is important in carcinogenesis, as it is a ubiquitously expressed receptor tyrosine kinase. Signal transducer and activator of transcription 3 (STAT3) is a master transcriptional regulator in proliferation and apoptosis. Our previous study demonstrated that the nuclear EGFR could b ...[more]