Ontology highlight
ABSTRACT:
SUBMITTER: Lalo U
PROVIDER: S-EPMC3844808 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Lalo Ulyana U Pankratov Yuri Y Wichert Sven P SP Rossner Moritz J MJ North R Alan RA Kirchhoff Frank F Verkhratsky Alexei A
The Journal of neuroscience : the official journal of the Society for Neuroscience 20080501 21
ATP plays an important role in signal transduction between neuronal and glial circuits and within glial networks. Here we describe currents activated by ATP in astrocytes acutely isolated from cortical brain slices by non-enzymatic mechanical dissociation. Brain slices were prepared from transgenic mice that express enhanced green fluorescent protein under the control of the human glial fibrillary acidic protein promoter. Astrocytes were studied by whole-cell voltage clamp. Exogenous ATP evoked ...[more]