Ontology highlight
ABSTRACT:
SUBMITTER: Moudi B
PROVIDER: S-EPMC3848338 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Moudi Bita B Salimi Saeedeh S Farajian Mashhadi Farzaneh F Sandoughi Mahnaz M Zakeri Zahra Z
TheScientificWorldJournal 20131114
<h4>Unlabelled</h4>FAS/FASL pathway plays a critical role in maintaining peripheral immune tolerance; therefore, the apoptosis genes, Fas and Fas ligand (FasL), could be suitable candidate genes in human SLE susceptibility.<h4>Materials and methods</h4>In this case-control study, 106 SLE patients and 149 sex, age, and ethnicity matched healthy controls were genotyped for the Fas A-670G and FasLC-844T polymorphisms by polymerase chain reaction-restriction fragment length polymorphism method (PCR- ...[more]