Dataset Information

Epidemiology and risk factors of chronic kidney disease in India - results from the SEEK (Screening and Early Evaluation of Kidney Disease) study.

ABSTRACT:

Background

There is a rising incidence of chronic kidney disease that is likely to pose major problems for both healthcare and the economy in future years. In India, it has been recently estimated that the age-adjusted incidence rate of ESRD to be 229 per million population (pmp), and >100,000 new patients enter renal replacement programs annually.

Methods

We cross-sectionally screened 6120 Indian subjects from 13 academic and private medical centers all over India. We obtained personal and medical history data through a specifically designed questionnaire. Blood and urine samples were collected.

Results

The total cohort included in this analysis is 5588 subjects. The mean ± SD age of all participants was 45.22 ± 15.2 years (range 18-98 years) and 55.1% of them were males and 44.9% were females. The overall prevalence of CKD in the SEEK-India cohort was 17.2% with a mean eGFR of 84.27 ± 76.46 versus 116.94 ± 44.65 mL/min/1.73 m2 in non-CKD group while 79.5% in the CKD group had proteinuria. Prevalence of CKD stages 1, 2, 3, 4 and 5 was 7%, 4.3%, 4.3%, 0.8% and 0.8%, respectively.

Conclusion

The prevalence of CKD was observed to be 17.2% with ~6% have CKD stage 3 or worse. CKD risk factors were similar to those reported in earlier studies.It should be stressed to all primary care physicians taking care of hypertensive and diabetic patients to screen for early kidney damage. Early intervention may retard the progression of kidney disease. Planning for the preventive health policies and allocation of more resources for the treatment of CKD/ESRD patients are imperative in India.

SUBMITTER: Singh AK

PROVIDER: S-EPMC3848478 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature

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Publications

Epidemiology and risk factors of chronic kidney disease in India - results from the SEEK (Screening and Early Evaluation of Kidney Disease) study.

Singh Ajay K AK Farag Youssef M K YM Mittal Bharati V BV Subramanian Kuyilan Karai KK Reddy Sai Ram Keithi SR Acharya Vidya N VN Almeida Alan F AF Channakeshavamurthy Anil A Ballal H Sudarshan HS P Gaccione G Issacs Rajan R Jasuja Sanjiv S Kirpalani Ashok L AL Kher Vijay V Modi Gopesh K GK Nainan Georgy G Prakash Jai J Rana Devinder Singh DS Sreedhara Rajanna R Sinha Dilip Kumar DK V Shah Bharat SB Sunder Sham S Sharma Raj K RK Seetharam Sridevi S Raju Tatapudi Ravi TR Rajapurkar Mohan M MM

BMC nephrology 20130528

<h4>Background</h4>There is a rising incidence of chronic kidney disease that is likely to pose major problems for both healthcare and the economy in future years. In India, it has been recently estimated that the age-adjusted incidence rate of ESRD to be 229 per million population (pmp), and >100,000 new patients enter renal replacement programs annually.<h4>Methods</h4>We cross-sectionally screened 6120 Indian subjects from 13 academic and private medical centers all over India. We obtained pe ...[more]

PMID: 23714169

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Dataset Information

Epidemiology and risk factors of chronic kidney disease in India - results from the SEEK (Screening and Early Evaluation of Kidney Disease) study.

Background

Methods

Results

Conclusion

Publications

Epidemiology and risk factors of chronic kidney disease in India - results from the SEEK (Screening and Early Evaluation of Kidney Disease) study.

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