Ontology highlight
ABSTRACT:
SUBMITTER: Davidoff C
PROVIDER: S-EPMC3848701 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Davidoff Candice C Payne Riley J RJ Willis Sharon H SH Doranz Benjamin J BJ Rucker Joseph B JB
Virology 20120917 2
To better understand how detergents disrupt enveloped viruses, we monitored the biophysical stability of murine leukemia virus (MLV) virus-like particles (VLPs) against a panel of commonly used detergents using real-time biosensor measurements. Although exposure to many detergents, such as Triton X-100 and Empigen, results in lysis of VLP membranes, VLPs appeared resistant to complete membrane lysis by a significant number of detergents, including Tween 20, Tween 80, Lubrol, and Saponin. VLPs ma ...[more]