Ontology highlight
ABSTRACT:
SUBMITTER: Grabli D
PROVIDER: S-EPMC3852420 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Grabli David D Karachi Carine C Welter Marie-Laure ML Lau Brian B Hirsch Etienne C EC Vidailhet Marie M François Chantal C
Journal of neurology, neurosurgery, and psychiatry 20120629 10
Gait and balance disorders represent a major therapeutic challenge in Parkinson's disease (PD). These symptoms respond poorly to dopaminergic treatments, except in the early phase of the disease. Currently, no other treatment is particularly efficient and rehabilitation appears to be the most effective approach. Since these gait and balance deficits are resistant to dopaminergic drugs, their occurrence could be related to the development of extradopaminergic lesions in PD patients. We provide a ...[more]