Ontology highlight
ABSTRACT:
SUBMITTER: Perez Parra S
PROVIDER: S-EPMC7111566 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Perez Parra Sahyli S McKay J Lucas JL Factor Stewart A SA
Movement disorders clinical practice 20200309 3
<h4>Background</h4>The relationship between freezing of gait (FOG) and levodopa response is complex. Some patients respond, some have no response and in some patients levodopa causes FOG. We present 2 cases demonstrating a diphasic worsening of FOG after levodopa dosing.<h4>Cases</h4>Two PD patients with FOG were examined during the practically defined <i>off</i> state, the transition from <i>off</i> to <i>on</i> (15 and 22 minutes postdose), and in the full <i>on</i> state (45 and 60 minutes po ...[more]