LigSearch: a knowledge-based web server to identify likely ligands for a protein target.
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ABSTRACT:
SUBMITTER: de Beer TA
PROVIDER: S-EPMC3852652 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
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LigSearch: a knowledge-based web server to identify likely ligands for a protein target.
de Beer Tjaart A P TA Laskowski Roman A RA Duban Mark-Eugene ME Chan A W Edith AW Anderson Wayne F WF Thornton Janet M JM
Acta crystallographica. Section D, Biological crystallography 20131119 Pt 12
Identifying which ligands might bind to a protein before crystallization trials could provide a significant saving in time and resources. LigSearch, a web server aimed at predicting ligands that might bind to and stabilize a given protein, has been developed. Using a protein sequence and/or structure, the system searches against a variety of databases, combining available knowledge, and provides a clustered and ranked output of possible ligands. LigSearch can be accessed at http://www.ebi.ac.uk/ ...[more]
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