Ontology highlight
ABSTRACT:
SUBMITTER: Lu JX
PROVIDER: S-EPMC3854443 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Lu Jian-xia JX Lu Zhong-qian ZQ Zhang Shao-lan SL Zhi Juan J Chen Zheng-ping ZP Wang Wan-xiang WX
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20130524 6
Single nucleotide polymorphisms in the promoter region of interleukin-18 (IL-18), an inflammatory cytokine, have been linked to susceptibility to many diseases, including cancer and immune dysfunction. Here, we explored the potential association between the IL-18 -607C/A (rs1946518) promoter region polymorphism and susceptibility to ischemic stroke (IS). This locus was amplified from peripheral blood samples of 386 IS patients (cases) and 364 healthy individuals (controls) by the polymerase chai ...[more]