Ontology highlight
ABSTRACT:
SUBMITTER: Jabbari A
PROVIDER: S-EPMC3858414 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Jabbari Ali A Suárez-Fariñas Mayte M Fuentes-Duculan Judilyn J Gonzalez Juana J Cueto Inna I Franks Andrew G AG Krueger James G JG
The Journal of investigative dermatology 20130614 1
Discoid lupus erythematosus (DLE) is the most common skin manifestation of lupus. Despite its high frequency in systemic lupus in addition to cases without extracutaneous manifestations, targeted treatments for DLE are lacking, likely because of a dearth of knowledge of the molecular landscape of DLE skin. Here, we profiled the transcriptome of DLE skin in order to identify signaling pathways and cellular signatures that may be targeted for treatment purposes. Further comparison of the DLE trans ...[more]