Ontology highlight
ABSTRACT:
SUBMITTER: Hartmann T
PROVIDER: S-EPMC3861659 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Hartmann Torsten T Zhang Bo B Baronian Grégory G Schulthess Bettina B Homerova Dagmar D Grubmüller Stephanie S Kutzner Erika E Gaupp Rosmarie R Bertram Ralph R Powers Robert R Eisenreich Wolfgang W Kormanec Jan J Herrmann Mathias M Molle Virginie V Somerville Greg A GA Bischoff Markus M
The Journal of biological chemistry 20131105 50
The tricarboxylic acid cycle (TCA cycle) is a central metabolic pathway that provides energy, reducing potential, and biosynthetic intermediates. In Staphylococcus aureus, TCA cycle activity is controlled by several regulators (e.g. CcpA, CodY, and RpiRc) in response to the availability of sugars, amino acids, and environmental stress. Developing a bioinformatic search for additional carbon catabolite-responsive regulators in S. aureus, we identified a LysR-type regulator, catabolite control pro ...[more]