Ontology highlight
ABSTRACT:
SUBMITTER: Allijn IE
PROVIDER: S-EPMC3863599 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Allijn Iris E IE Leong Wei W Tang Jun J Gianella Anita A Mieszawska Aneta J AJ Fay Francois F Ma Ge G Russell Stewart S Callo Catherine B CB Gordon Ronald E RE Korkmaz Emine E Post Jan Andries JA Zhao Yiming Y Gerritsen Hans C HC Thran Axel A Proksa Roland R Daerr Heiner H Storm Gert G Fuster Valentin V Fisher Edward A EA Fayad Zahi A ZA Mulder Willem J M WJ Cormode David P DP
ACS nano 20131017 11
Low-density lipoprotein (LDL) plays a critical role in cholesterol transport and is closely linked to the progression of several diseases. This motivates the development of methods to study LDL behavior from the microscopic to whole-body level. We have developed an approach to efficiently load LDL with a range of diagnostically active nanocrystals or hydrophobic agents. We performed focused experiments on LDL labeled with gold nanocrystals (Au-LDL). The labeling procedure had minimal effect on L ...[more]