Ontology highlight
ABSTRACT:
SUBMITTER: Leeper NJ
PROVIDER: S-EPMC6113536 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Leeper Nicholas J NJ Park Seung-Min SM Smith Bryan Ronain BR
JACC. Basic to translational science 20170227 1
Nanoparticles promise to advance the field of cardiovascular theranostics. However, their sustained and targeted delivery remains an important obstacle. The body synthesizes some "natural" nanoparticles, including high-density lipoprotein (HDL), which may home to the atherosclerotic plaque and promote cholesterol efflux. In a recent article published in <i>JACC: Cardiovascular Imaging</i>, investigators generated modified, radiolabeled HDL nanoparticles and confirmed they accumulated in atherosc ...[more]