Ontology highlight
ABSTRACT:
SUBMITTER: Li S
PROVIDER: S-EPMC3865644 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Li Shan S Niu Xiaoyin X Xi Yebin Y Deng Shaohua S Li Chengzhen C Zhao Qing Q Chen Guangjie G
Clinical & developmental immunology 20131202
The aim of this study is to determine whether the regulatory role of T cell vaccination (TCV) is through inhibition of Th1/Th17/Tfh and production of autoantibodies on collagen-induced arthritis (CIA). First, CIA mice were treated with TCV. After disease onset, the incidence and severity of change in joint histopathology were evaluated. Mice in the TCV-treated group showed less disease severity and less infiltration of inflammatory cells in the joint sections. TCV decreased the frequencies of Th ...[more]