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ABSTRACT: Objective
Since there is a paucity of reference data in the literature to indicate the relationship between HbA1c, and 24 h mean blood glucose (MBG) from continuous glucose monitoring (CGM) in Chinese populations, we described the above relationship in adult Chinese subjects with different glucose tolerance status.Methods
Seven-hundred-and-forty-two individuals without history of diabetes were included to the study at 11 hospitals in urban areas across China from 2007-2009 and data of 673 subjects were included into the final analysis. Oral glucose tolerance test (OGTT) classified the participants as nondiabetic subjects, including those with normal glucose regulation (NGR; n?=?121) and impaired glucose regulation (IGR; n?=?209), or newly diagnosed type 2 diabetes (n?=?343). All participants completed testing for HbA1c levels and wore a CGM system for three consecutive days. The 24 h MBG levels were calculated. Spearman correlations and linear regression analyses were applied to quantify the relationship between glucose markers.Results
The levels of HbA1c and 24 h MBG significantly increased with presence of glucose intolerance (NGR
SUBMITTER: Zhou J
PROVIDER: S-EPMC3871656 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Zhou Jian J Mo Yifei Y Li Hong H Ran Xingwu X Yang Wenying W Li Qiang Q Peng Yongde Y Li Yanbing Y Gao Xin X Luan Xiaojun X Wang Weiqing W Xie Yun Y Jia Weiping W
PloS one 20131223 12
<h4>Objective</h4>Since there is a paucity of reference data in the literature to indicate the relationship between HbA1c, and 24 h mean blood glucose (MBG) from continuous glucose monitoring (CGM) in Chinese populations, we described the above relationship in adult Chinese subjects with different glucose tolerance status.<h4>Methods</h4>Seven-hundred-and-forty-two individuals without history of diabetes were included to the study at 11 hospitals in urban areas across China from 2007-2009 and da ...[more]