Ontology highlight
ABSTRACT:
SUBMITTER: Park HJ
PROVIDER: S-EPMC3871704 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Park Hae Jeong HJ Kim Su Kang SK Kim Jong Woo JW Lee Sang Hyub SH Yoo Koo Han KH Chung Joo-Ho JH
Disease markers 20131209 6
Fibroblast growth factors (FGFs) and their receptors (FGFRs) have been implicated in prostate growth and are overexpressed in benign prostatic hyperplasia (BPH). In this study, we investigated whether single nucleotide polymorphisms (SNPs) of the FGFR genes (FGFR1 and FGFR2) were associated with BPH and its clinical phenotypes in a population of Korean men. We genotyped four SNPs in the exons of FGFR1 and FGFR2 (rs13317 in FGFR1; rs755793, rs1047100, and rs3135831 in FGFR2) using direct sequenci ...[more]