Ontology highlight
ABSTRACT:
SUBMITTER: Symes AJ
PROVIDER: S-EPMC3874000 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Symes Andrew J AJ Eilertsen Marte M Millar Michael M Nariculam Joseph J Freeman Alex A Notara Maria M Feneley Mark R MR Patel Hitendra R H HR Masters John R W JR Ahmed Aamir A
PloS one 20131227 12
Prostate carcinoma is the most common cancer in men with few, quantifiable, biomarkers. Prostate cancer biomarker discovery has been hampered due to subjective analysis of protein expression in tissue sections. An unbiased, quantitative immunohistochemical approach provided here, for the diagnosis and stratification of prostate cancer could overcome this problem. Antibodies against four proteins BTF3, HINT1, NDRG1 and ODC1 were used in a prostate tissue array (> 500 individual tissue cores from ...[more]