Ontology highlight
ABSTRACT:
SUBMITTER: Mordini S
PROVIDER: S-EPMC3874003 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Mordini Serena S Osera Cecilia C Marini Simone S Scavone Francesco F Bellazzi Riccardo R Galizzi Alessandro A Calvio Cinzia C
PloS one 20131227 12
In B. subtilis swarming and robust swimming motility require the positive trigger of SwrA on fla/che operon expression. Despite having an essential and specific activity, how SwrA executes this task has remained elusive thus far. We demonstrate here that SwrA acts at the main σ(A)-dependent fla/che promoter PA(fla/che) through DegU. Electrophoretic mobility shift assays (EMSA) reveal that SwrA forms a complex with the phosphorylated form of DegU (DegU~P) at PA(fla/che) while it is unable to do s ...[more]