Ontology highlight
ABSTRACT:
SUBMITTER: Basta HA
PROVIDER: S-EPMC3878079 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Basta Holly A HA Ashraf Shamaila S Sgro Jean-Yves JY Bochkov Yury A YA Gern James E JE Palmenberg Ann C AC
Virology 20131020
Human rhinoviruses of the RV-C species are recently discovered pathogens with greater clinical significance than isolates in the RV-A+B species. The RV-C cannot be propagated in typical culture systems; so much of the virology is necessarily derivative, relying on comparative genomics, relative to the better studied RV-A+B. We developed a bioinformatics-based structural model for a C15 isolate. The model showed the VP1-3 capsid proteins retain their fundamental cores relative to the RV-A+B, but ...[more]