Ontology highlight
ABSTRACT:
SUBMITTER: Stephens SH
PROVIDER: S-EPMC3878876 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Stephens Sarah H SH Franks Alexis A Berger Ralph R Palionyte Milda M Fingerlin Tasha E TE Wagner Brandie B Logel Judith J Olincy Ann A Ross Randal G RG Freedman Robert R Leonard Sherry S
Psychiatric genetics 20120201 1
<h4>Objective</h4>The chromosomal region, 15q13-q14, including the α7 nicotinic acetylcholine receptor gene, CHRNA7, is a replicated region for schizophrenia. This study fine-mapped genes at 15q13-q14 to determine whether the association is unique to CHRNA7.<h4>Methods</h4>Family-based and case-control association studies were performed on Caucasian-non-Hispanic and African-American individuals from 120 families as well as 468 individual patients with schizophrenia and 144 well-characterized con ...[more]