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Evidence for continuing cross-species transmission of SIVsmm to humans: characterization of a new HIV-2 lineage in rural Cote d'Ivoire.


ABSTRACT: HIV types 1 and 2 (HIV-1 and HIV-2) are the result of multiple cross-species transmissions of their simian counterparts (SIVs) to humans. We studied whether new SIVs lineages have been transmitted to humans in rural Côte d'Ivoire and identified a novel HIV-2 variant (HIV-2-07IC-TNP03) not related to any of the previously defined HIV-2 groups. This finding shows that sooty mangabey viruses continue to be transmitted to humans, causing new zoonotic outbreaks.

SUBMITTER: Ayouba A 

PROVIDER: S-EPMC3881176 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature

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Evidence for continuing cross-species transmission of SIVsmm to humans: characterization of a new HIV-2 lineage in rural Côte d'Ivoire.

Ayouba Ahidjo A   Akoua-Koffi Chantal C   Calvignac-Spencer Sébastien S   Esteban Amandine A   Locatelli Sabrina S   Li Hui H   Li Yingying Y   Hahn Beatrice H BH   Delaporte Eric E   Leendertz Fabian H FH   Peeters Martine M  

AIDS (London, England) 20130901 15


HIV types 1 and 2 (HIV-1 and HIV-2) are the result of multiple cross-species transmissions of their simian counterparts (SIVs) to humans. We studied whether new SIVs lineages have been transmitted to humans in rural Côte d'Ivoire and identified a novel HIV-2 variant (HIV-2-07IC-TNP03) not related to any of the previously defined HIV-2 groups. This finding shows that sooty mangabey viruses continue to be transmitted to humans, causing new zoonotic outbreaks. ...[more]

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