Ontology highlight
ABSTRACT:
SUBMITTER: Zhao B
PROVIDER: S-EPMC3883121 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Zhao Bing B Wang Hongliang H Zong Gang G Li Ping P
BMC neurology 20131227
<h4>Background</h4>Interferon induced transmembrane protein 3 (IFITM3) is transcribed in most tissues and highly interferon-inducible. However, the role of IFITM3 in cancer is still poorly understood.<h4>Methods</h4>Expression levels of IFITM3 were analyzed in 60 glioma patients by immunohistochemistry (IHC). Following closely, we investigated the phenotype of IFITM3 knockdown on glioma cell growth and tumorigenesis in vitro using lentivirus-mediated loss-of-function strategy.<h4>Results</h4>Dep ...[more]