Schistosomiasis japonica during pregnancy is associated with elevated endotoxin levels in maternal and placental compartments.
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ABSTRACT:
SUBMITTER: McDonald EA
PROVIDER: S-EPMC3883168 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
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Schistosomiasis japonica during pregnancy is associated with elevated endotoxin levels in maternal and placental compartments.
McDonald Emily A EA Pond-Tor Sunthorn S Jarilla Blanca B Sagliba Marianne J MJ Gonzal Annaliza A Amoylen Amabelle J AJ Olveda Remigio R Acosta Luz L Gundogan Fusun F Ganley-Leal Lisa M LM Kurtis Jonathan D JD Friedman Jennifer F JF
The Journal of infectious diseases 20130820 3
Schistosomiasis affects approximately 40 million women of reproductive age and has been linked to elevated levels of circulating endotoxin in nonpregnant individuals. We have evaluated endotoxin levels in maternal, placental, and newborn blood collected from women residing in Leyte, Philippines. Endotoxin levels in both maternal and placental compartments in pregnant women with schistosomiasis were 1.3- and 2.4-fold higher, respectively, than in uninfected women. In addition, higher concentratio ...[more]
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