Ontology highlight
ABSTRACT:
SUBMITTER: Zhu C
PROVIDER: S-EPMC3885172 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Tetrahedron letters 20140101 1
We describe an oxidative Strecker reaction that allows for direct cyanation of <i>para</i>-methoxyphenyl (PMP)-protected primary amines. A vanadium(V) complex was used as the catalyst and TBHP as the oxidant. The cyanation occurs at the α-C position bearing either an alkyl or an aromatic group. This method provides a direct access to α-aminonitrile from amines with one-carbon extension. ...[more]