The pattern and distribution of deleterious mutations in maize.
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ABSTRACT:
SUBMITTER: Mezmouk S
PROVIDER: S-EPMC3887532 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Publications
The pattern and distribution of deleterious mutations in maize.
Mezmouk Sofiane S Ross-Ibarra Jeffrey J
G3 (Bethesda, Md.) 20140110 1
Most nonsynonymous mutations are thought to be deleterious because of their effect on protein sequence and are expected to be removed or kept at low frequency by the action of natural selection. Nonetheless, the effect of positive selection on linked sites or drift in small or inbred populations may also impact the evolution of deleterious alleles. Despite their potential to affect complex trait phenotypes, deleterious alleles are difficult to study precisely because they are often at low freque ...[more]
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