Design and Synthesis of a New Class of Twin-Chain Amphiphiles for Self-Assembled Monolayer-based Electrochemical Biosensor Applications.
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ABSTRACT:
SUBMITTER: Fisher TJ
PROVIDER: S-EPMC3888879 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
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Design and Synthesis of a New Class of Twin-Chain Amphiphiles for Self-Assembled Monolayer-based Electrochemical Biosensor Applications.
Fisher Thomas J TJ Cañete Socrates Jose P SJ Lai Rebecca Y RY Dussault Patrick H PH
European journal of organic chemistry 20130601 16
A new class of twin-chain hydroxyalkylthiols (mercaptoalkanols) featuring a nearly constant cross-section and the potential for modification of one or both termini are available with complete regioselectivity through Pd-mediated couplings of benzene diiododitriflate, including an example of a previously unreported coupling to generate an ortho-substituted arene bis acetic acid. Self-assembled monolayers (SAMs) prepared from the new amphiphiles demonstrate improved stability in an electrochemical ...[more]
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