Ontology highlight
ABSTRACT:
SUBMITTER: Perathoner S
PROVIDER: S-EPMC3894163 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Perathoner Simon S Daane Jacob M JM Henrion Ulrike U Seebohm Guiscard G Higdon Charles W CW Johnson Stephen L SL Nüsslein-Volhard Christiane C Harris Matthew P MP
PLoS genetics 20140116 1
The scaling relationship between the size of an appendage or organ and that of the body as a whole is tightly regulated during animal development. If a structure grows at a different rate than the rest of the body, this process is termed allometric growth. The zebrafish another longfin (alf) mutant shows allometric growth resulting in proportionally enlarged fins and barbels. We took advantage of this mutant to study the regulation of size in vertebrates. Here, we show that alf mutants carry gai ...[more]