Ontology highlight
ABSTRACT:
SUBMITTER: Daina G
PROVIDER: S-EPMC3895626 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Daina Gemma G Ramos Laia L Rius Mariona M Obradors Albert A Del Rey Javier J Giralt Magda M Campillo Mercedes M Velilla Esther E Pujol Aïda A Martinez-Pasarell Olga O Benet Jordi J Navarro Joaquima J
European journal of human genetics : EJHG 20130522 2
Aneuploidy has been a major issue in human gametes and is closely related to fertility problems, as it is known to be present in cleavage stage embryos and gestational losses. Pre-meiotic chromosome abnormalities in women have been previously described. The aim of this study is to assess the whole-chromosome complement in immature oocytes to find those abnormalities caused by mitotic instability. For this purpose, a total of 157 oocytes at the germinal vesicle or metaphase I stage, and discarded ...[more]