Silica: An efficient catalyst for one-pot regioselective synthesis of dithioethers.

ABSTRACT: The development of a silica-promoted highly selective synthesis of 1,2 or 1,3-dithioethers via solvent-free one-pot tandem reactions of an allyl bromide with excess thiol at room temperature is described. The choice of silica gel, either pre-calcined or moistened with water, exhibited notable regioselectivity in the formation of dithioethers. Plausible mechanistic routes were explored and postulated.

SUBMITTER: Kundu S 

PROVIDER: S-EPMC3896229 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature