Ontology highlight
ABSTRACT:
SUBMITTER: Chen H
PROVIDER: S-EPMC3896609 | biostudies-literature | 2013 Nov-Dec
REPOSITORIES: biostudies-literature
Chen Hao H Ding Xiuyun X Gao Yuan Y Jiang Xiaohua X Liu Xiaolan X Chen Yong Y Gao Jianen J Zhou Xiaping X Cai Zhiming Z Sun Qihong Q
mAbs 20130822 6
Vascular endothelial growth factor receptor 3 (VEGFR-3) is a receptor for the vascular endothelial growth factor C and D (VEGF-C and D) and plays a critical role in the development of embryonic vascular system and regulation of tumor lymphangiogenesis. In this report, we generated a novel panel of 17 monoclonal antibodies (mAbs) against human VEGFR-3 and determined their ability to inhibit the proliferation of human erythroleukemia (HEL) cells and angiogenesis of chick embryo chorioallantoic mem ...[more]