Ontology highlight
ABSTRACT:
SUBMITTER: Mejia-Leon ME
PROVIDER: S-EPMC3898044 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Mejía-León María Esther ME Petrosino Joseph F JF Ajami Nadim Jose NJ Domínguez-Bello María Gloria MG de la Barca Ana María Calderón AM
Scientific reports 20140122
Dysbiosis of the intestinal microbiota affecting the gut barrier could be triggering Type 1 Diabetes (T1D), the second most frequent autoimmune disease in childhood. This study compared the structure of the fecal microbiota in 29 mestizo children aged 7-18 years, including 8 T1D at onset, 13 T1D after 2 years treatment, and 8 healthy controls. Clinical information was collected, predisposing haplotypes were determined; the fecal DNA was extracted, the V4 region of the 16S rRNA gene amplified and ...[more]