Ontology highlight
ABSTRACT:
SUBMITTER: de Groot PF
PROVIDER: S-EPMC5718513 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
de Groot Pieter F PF Belzer Clara C Aydin Ömrüm Ö Levin Evgeni E Levels Johannes H JH Aalvink Steven S Boot Fransje F Holleman Frits F van Raalte Daniël H DH Scheithauer Torsten P TP Simsek Suat S Schaap Frank G FG Olde Damink Steven W M SWM Roep Bart O BO Hoekstra Joost B JB de Vos Willem M WM Nieuwdorp Max M
PloS one 20171206 12
<h4>Objective</h4>Environmental factors driving the development of type 1 diabetes (T1D) are still largely unknown. Both animal and human studies have shown an association between altered fecal microbiota composition, impaired production of short-chain fatty acids (SCFA) and T1D onset. However, observational evidence on SCFA and fecal and oral microbiota in adults with longstanding T1D vs healthy controls (HC) is lacking.<h4>Research design and methods</h4>We included 53 T1D patients without com ...[more]