Ontology highlight
ABSTRACT:
SUBMITTER: Gonzalez S
PROVIDER: S-EPMC3900305 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
González Sheyla S Deng Sophie X SX
Experimental eye research 20130907
Niche factors are important in the maintenance and regulation of stem cells. Limbal stromal cells are potentially a component of limbal stem cell (LSC) niche. We investigated the role of the limbal stromal cells in the ex vivo expansion of limbal stem/progenitor cells. Limbal epithelial cells were cultured as single-cell suspension and cell clusters from dispase II or collagenase A (ColA), or tissue explant. ColA isolated limbal stromal cells along with limbal epithelial cells. In the presence o ...[more]