Ontology highlight
ABSTRACT:
SUBMITTER: Wasalathanthri DP
PROVIDER: S-EPMC3901045 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Wasalathanthri Dhanuka P DP Malla Spundana S Bist Itti I Tang Chi K CK Faria Ronaldo C RC Rusling James F JF
Lab on a chip 20131201 23
A high throughput electrochemiluminescent (ECL) chip was fabricated and integrated into a fluidic system for screening toxicity-related chemistry of drug and pollutant metabolites. The chip base is conductive pyrolytic graphite onto which are printed 64 microwells capable of holding one-μL droplets. Films combining DNA, metabolic enzymes and an ECL-generating ruthenium metallopolymer (Ru(II)PVP) are fabricated in these microwells. The system runs metabolic enzyme reactions, and subsequently dete ...[more]