Ontology highlight
ABSTRACT:
SUBMITTER: Lacy ER
PROVIDER: S-EPMC390366 | biostudies-literature | 2004
REPOSITORIES: biostudies-literature
Lacy Eilyn R ER Nguyen Binh B Le Minh M Cox Kari K KK OHare Caroline C Hartley John A JA Lee Moses M Wilson W David WD
Nucleic acids research 20040402 6
To complement available structure and binding results and to develop a detailed understanding of the basis for selective molecular recognition of T.G mismatches in DNA by imidazole containing polyamides, a full thermodynamic profile for formation of the T.G-polyamide complex has been determined. The amide-linked heterocycles f-ImImIm and f-PyImIm (where f is formamido group, Im is imidazole and Py is pyrrole) were studied by using biosensor-surface plasmon resonance (SPR) and isothermal titratio ...[more]