Ontology highlight
ABSTRACT:
SUBMITTER: DeMaster LK
PROVIDER: S-EPMC3904427 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
DeMaster Laura K LK Rose Timothy M TM
Virology 20131029
KSHV establishes characteristic latent infections in vitro, while RRV, a related macaque rhadinovirus, establishes characteristic permissive infections with virus replication. We identified cells that are not permissive for RRV replication and recapitulate the latent KSHV infection and reactivation processes. The RRV replication and transactivator (Rta) promoter was characterized in permissive and non-permissive cells and compared to the KSHV Rta promoter. Both promoters contained a critical Sp1 ...[more]