Ontology highlight
ABSTRACT:
SUBMITTER: Yang TL
PROVIDER: S-EPMC3904876 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Yang Tsung-Lin TL Lin Lin L Lou Pei-Jen PJ Chang Ta-Chau TC Young Tai-Horng TH
PloS one 20140128 1
Cancer can be easily treated when found early. A probe capable of detecting cell transformation may increase the success rate of early diagnosis of cancer. In this report we have tested the ability of a fluorescent, quadruplex DNA binding probe, 3,6-bis(1-methyl-4- vinylpyridinium) carbazole diiodide (BMVC), to detect cell transformation in vitro. BMVC was applied to living cells in several different models of cell transformation, and the fluorescence signals of BMVC were measured. The degrees o ...[more]