Ontology highlight
ABSTRACT:
SUBMITTER: Zanzoni A
PROVIDER: S-EPMC3905859 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Zanzoni Andreas A Marchese Domenica D Agostini Federico F Bolognesi Benedetta B Cirillo Davide D Botta-Orfila Maria M Livi Carmen Maria CM Rodriguez-Mulero Silvia S Tartaglia Gian Gaetano GG
Nucleic acids research 20130903 22
Previous evidence indicates that a number of proteins are able to interact with cognate mRNAs. These autogenous associations represent important regulatory mechanisms that control gene expression at the translational level. Using the catRAPID approach to predict the propensity of proteins to bind to RNA, we investigated the occurrence of autogenous associations in the human proteome. Our algorithm correctly identified binding sites in well-known cases such as thymidylate synthase, tumor suppress ...[more]