Ontology highlight
ABSTRACT:
SUBMITTER: Xiong Y
PROVIDER: S-EPMC3906264 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Xiong Yongzhen Y Chen Shengli S Chen Ruhong R Lin Weiyan W Ni Jindong J
Human vaccines & immunotherapeutics 20130604 8
To investigate whether selected single nucleotide polymorphisms (SNPs) in miR-146a, miR-196a2, miR-27a, miR-26a-1, miR-124 and miR-149 genes are associated with immune response to hepatitis B vaccine. The genotype and allele frequencies of SNPs were compared between the non-responders (n=77) and responders (n=207). The associations of the genotypes with antibody levels were assessed in the responders. Significant associations were observed between SNPs in miR-146a and miR-26a-1 genes and non-res ...[more]