Ontology highlight
ABSTRACT:
SUBMITTER: Danczak-Pazdrowska A
PROVIDER: S-EPMC3907897 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Dańczak-Pazdrowska Aleksandra A Kowalczyk Michał J MJ Szramka-Pawlak Beata B Gornowicz-Porowska Justyna J Szewczyk Aleksandra A Silny Wojciech W Molińska-Glura Marta M Olewicz-Gawlik Anna A Zaba Ryszard R Pazdrowski Jakub J Hrycaj Paweł P
Postepy dermatologii i alergologii 20131218 6
<h4>Introduction</h4>Morphea (localized scleroderma) is a rare cutaneous disease characterized by skin fibrosis of unknown pathogenesis. Transforming growth factor-β (TGF-β) is a potent profibrotic factor. The role of TGF-β in morphea remains unclear.<h4>Aim</h4>The goal of this study was to estimate the expression level of TGF-β1 in skin and peripheral blood mononuclear cells as well as the plasma levels of TGF-β1 in plaque morphea (MEP).<h4>Material and methods</h4>The study involved 20 MEP pa ...[more]