Ontology highlight
ABSTRACT:
SUBMITTER: Qiu W
PROVIDER: S-EPMC3910486 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
BioMed research international 20140108
Salivary duct carcinoma (SDC) is an aggressive malignant tumor with a high mortality, which resembles high-grade breast ductal carcinoma in morphology. The parotid gland is the most common location. Its molecular genetic characteristics remain largely unknown. We have previously reported high incidence of PIK3CA somatic mutations in head and neck squamous cell carcinoma, particularly in pharyngeal cancers. Here we examined the PIK3CA gene expression status and hotspot mutations in six cases of S ...[more]