Ontology highlight
ABSTRACT:
SUBMITTER: Votteler M
PROVIDER: S-EPMC3912871 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Votteler Miriam M Berrio Daniel A Carvajal DA Horke Alexander A Sabatier Laetitia L Reinhardt Dieter P DP Nsair Ali A Aikawa Elena E Schenke-Layland Katja K
Development (Cambridge, England) 20130501 11
Semilunar valve leaflets have a well-described trilaminar histoarchitecture, with a sophisticated elastic fiber network. It was previously proposed that elastin-containing fibers play a subordinate role in early human cardiac valve development; however, this assumption was based on data obtained from mouse models and human second and third trimester tissues. Here, we systematically analyzed tissues from human fetal first (4-12 weeks) and second (13-18 weeks) trimester, adolescent (14-19 years) a ...[more]