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The association between cortisol and neighborhood disadvantage in a U.S. population-based sample of adolescents.


ABSTRACT: The association between neighborhood conditions and cortisol is rarely studied in children or adolescents and has been hampered by small sample size and racial/ethnic and geographic homogeneity. Our objective was to estimate the association between neighborhood disadvantage and salivary cortisol levels in a large, geographically and racially/ethnically diverse sample of adolescents from the National Comorbidity Survey Replication Adolescent Supplement. Salivary cortisol was collected before and after an interview administered in the adolescent's home. We used a propensity score approach to match adolescents living in disadvantaged neighborhoods with those in non-disadvantaged neighborhoods to create two similar groups based on the time and day of cortisol collection as well as demographic characteristics. Adolescents living in disadvantaged neighborhoods had higher pre-interview cortisol levels and steeper rates of decline in cortisol levels over the course of the interview than similar adolescents in non-disadvantaged neighborhoods. This bolsters the evidence base suggesting that place may influence the stress response system.

SUBMITTER: Rudolph KE 

PROVIDER: S-EPMC3913161 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature

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The association between cortisol and neighborhood disadvantage in a U.S. population-based sample of adolescents.

Rudolph Kara E KE   Wand Gary S GS   Stuart Elizabeth A EA   Glass Thomas A TA   Marques Andrea H AH   Duncko Roman R   Merikangas Kathleen R KR  

Health & place 20131120


The association between neighborhood conditions and cortisol is rarely studied in children or adolescents and has been hampered by small sample size and racial/ethnic and geographic homogeneity. Our objective was to estimate the association between neighborhood disadvantage and salivary cortisol levels in a large, geographically and racially/ethnically diverse sample of adolescents from the National Comorbidity Survey Replication Adolescent Supplement. Salivary cortisol was collected before and  ...[more]

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