Ontology highlight
ABSTRACT:
SUBMITTER: Okudela K
PROVIDER: S-EPMC3913595 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Okudela Koji K Katayama Akira A Woo Tetsukan T Mitsui Hideaki H Suzuki Takehisa T Tateishi Yoko Y Umeda Shigeaki S Tajiri Michihiko M Masuda Munetaka M Nagahara Noriyuki N Kitamura Hitoshi H Ohashi Kenichi K
PloS one 20140204 2
This study investigated the proteome modulated by oncogenic KRAS in immortalized airway epithelial cells. Chloride intracellular channel protein 4 (CLIC4), S100 proteins (S100A2 and S100A11), tropomyosin 2, cathepsin L1, integrinsα3, eukaryotic elongation factor 1, vimentin, and others were discriminated. We here focused on CLIC4 to investigate its potential involvement in carcinogenesis in the lung because previous studies suggested that some chloride channels and chloride channel regulators co ...[more]