Ontology highlight
ABSTRACT:
SUBMITTER: Santos J
PROVIDER: S-EPMC4468336 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Santos Joana J Mesquita Diana D Barros-Silva João D JD Jerónimo Carmen C Henrique Rui R Morais António A Paulo Paula P Teixeira Manuel R MR
Oncoscience 20150317 5
Gastrin-releasing peptide receptor (GRPR) is known to be overexpressed in several human malignancies, including prostate cancer, and has been implicated in multiple important neoplastic signaling pathways. We recently have shown that GRPR is an ERG and ETV1 target gene in prostate cancer, using a genome-wide scale and exon-level expression microarray platform. Due to its cellular localization, the relevance of its function and the availability of blocking agents, GRPR seems to be a promising can ...[more]