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Pimobendan B from powder diffraction data.

ABSTRACT: The title mol-ecule, C19H18N4O2 {systematic name: (RS)-6-[2-(4-meth-oxy-phen-yl)-1H-benzimidazol-5-yl]-5-methyl-4,5-di-hydro-pyridazin-3(2H)-one}, adopts an extended conformation. The dihedral angles between the central benzimidazole ring sytem and the pendant meth-oxy-phenyl and pyridazinone residues are 1.41?(18) and 9.7?(3)°, respectively. In the crystal, N-H?N hydrogen bonds link the imadazole groups into [001] chains, and pairs of N-H?O hydrogen bonds link the pyridazinone groups into dimers. Together, these generate a two-dimensional supra-molecular structure parallel to (010). The layers are linked by C-H?? inter-actions.

SUBMITTER: Zvirgzdins A

PROVIDER: S-EPMC3919548 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature

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Pimobendan B from powder diffraction data.

Zvirgzdins Alvis A Delina Mara M Mishnev Anatoly A Actins Andris A

Acta crystallographica. Section E, Structure reports online 20131019 Pt 11

The title mol-ecule, C19H18N4O2 {systematic name: (RS)-6-[2-(4-meth-oxy-phen-yl)-1H-benzimidazol-5-yl]-5-methyl-4,5-di-hydro-pyridazin-3(2H)-one}, adopts an extended conformation. The dihedral angles between the central benzimidazole ring sytem and the pendant meth-oxy-phenyl and pyridazinone residues are 1.41 (18) and 9.7 (3)°, respectively. In the crystal, N-H⋯N hydrogen bonds link the imadazole groups into [001] chains, and pairs of N-H⋯O hydrogen bonds link the pyridazinone groups into dimer ...[more]

PMID: 24526935

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