Ontology highlight
ABSTRACT:
SUBMITTER: McNeil BA
PROVIDER: S-EPMC3919590 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
McNeil Bonnie A BA Simon Dawn M DM Zimmerly Steven S
Nucleic acids research 20131108 3
Group II introns are ribozymes and retroelements found in bacteria, and are thought to have been the ancestors of nuclear pre-mRNA introns. Whereas nuclear introns undergo prolific alternative splicing in some species, group II introns are not known to carry out equivalent reactions. Here we report a group II intron in the human pathogen Clostridium tetani, which undergoes four alternative splicing reactions in vivo. Together with unspliced transcript, five mRNAs are produced, each encoding a di ...[more]